SaProt
Creates protein embeddings that use structure as well as sequence.
- Field
- Biology & genomics
- Method
- Foundation model
- Data it takes
- sequence, structure
- License
- MIT AND GPL-3.0 — restricted use
SaProt encodes each residue using both its amino acid and its local structural context, via the 3Di alphabet from foldseek. Where ESM C uses sequence alone, SaProt also uses structure.
This benefits tasks where function depends more on shape than on sequence similarity.
The container bundles foldseek, so the license is part MIT and part GPL-3.0.
Catalog entry last checked 2026-08-17. All models →
Run SaProt on your data
The lab runs this on its own compute, in a container, with the inputs and parameters recorded alongside the result. Initial scoping conversations are free.
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